Management options for prostate cancer depends on the cancer stage, presence of high risk features and patient’s life expectancy
Estimate the patient’s life expectancy.
Limited life expectancy< 5 years: consider watchful waiting or palliative androgen deprivation therapy.
Life expectancy> 5 years: Manage according to cancer stage
Seven standard treatment used
Management options include:
1. Watchful waiting and Active surveillance – is indicated to those with limited life expectancy, slow growing tumor and asymptomatic or minimal symptoms. It involves regular scheduled digital rectal examination and checking PSA levels. In addition, active surveillance includes prostate biopsy and MRI.If there is disease progression treatment is initiated.
2. Surgery
Patients with good health and whose tumor is in the prostate gland only may be treated with surgery to remove the tumor.
3. Radiation therapy
This therapy uses high energy x-rays to kill cancer cells or keep them from growing. Can be internal (brachytherapy) or external beam radiation therapy.
4. Hormone therapy
Patients with advanced prostate cancer usually receive hormone therapy.
In addition, a man with early stage prostate cancer may have hormone therapy before during and after radiation therapy. Hormone therapy may also be given after surgery.
This treatment removes hormones or blocks their action and stops cancer from growing. An example of a drug used in the hormone therapy is Goserelin a Luteinizing hormone releasing hormone agonist which stop testes from producing testosterone.
5. Chemotherapy
Uses drugs to stop the growth of cancer cells either by killing the cancer cells or stopping them from dividing. An example of a drug used is docetaxel.
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